Research Senior Scientist, Bioanalytical

We need your talent!

Do you want to help shape the future of biopharmaceutical innovation? At Waters Corporation, one of the world’s leading technology providers of analytical tools in the life sciences and biopharma industries, we are driven by a passion for enabling scientific breakthroughs. With more than 7,000 employees worldwide, Waters is dedicated to delivering technologies that empower scientists to produce safe, effective, and high-quality biotherapeutics.

We are seeking a highly motivated scientist to join our state-of-the-art Immerse Delaware Lab at the University of Delaware’s Science, Technology and Advanced Research (STAR) Campus. This is a unique opportunity to contribute to cutting-edge research that advances next-generation bioprocess technologies.

At Immerse Delaware, you will be part of a collaborative ecosystem of chemists, bioprocess engineers, and data scientists, working with access to the latest small- and large-scale bioreactors, analytical instrumentation, and bioanalytical tools. Together, we’re uncovering new trends and opportunities in bioprocess monitoring, control, and analytical characterization of biologics and novel modalities.

Our mission is to tackle the most significant challenges in the biopharmaceutical industry through partnerships across academia and industry, including dynamic collaborations with the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL), universities, and companies worldwide.

If you’re inspired by challenging, cutting-edge science and want to see your ideas translate into technologies and therapies that make a global impact — join us.

This role reports to the Global Research Organization at Waters and offers the opportunity to leverage your technical expertise, creativity, and curiosity to help bring the next generation of bioprocessing innovations to life.

The meaningful work you will do: 

Innovative Biomanufacturing Solutions: Collaborate with cell culture scientists to develop advanced analytical workflows, novel sensors/probes, and predictive models to address challenges in process optimization, monitoring, and control.

Protein Characterization & Chromatography: Evaluate protein stability, variants, and glycan profiles. Apply and optimize chromatographic and mass spectrometric techniques to analyze complex biological samples and troubleshoot analytical challenges.

Prototype & Proof-of-Concept Development: Design and execute PoC studies, analyze data, and support bioprocess monitoring and analytical development.

Process Analytical Technology (PAT): Support the design and implementation of PAT tools for real-time bioprocess control.

Customer Insight: Understand customer workflows and analytical needs to inform next-generation scientific instrumentation.

Innovation & Leadership: Drive new scientific concepts and provide strategic input to R&D initiatives.

Education:

o Ph.D. in Analytical Biochemistry, Biophysics, Biochemistry, or Biomedical Engineering, or

o Master’s with 3+ years, or Bachelor’s with 5+ years of relevant experience.

· Technical Expertise:

o Hands-on experience in chromatography, protein characterization, and mass spectrometry (e.g., quadrupole, TOF, ion trap).

o Strong experimental design and data interpretation skills supporting upstream bioprocess development.

· Analytical & Laboratory Skills:

o Proficient in SDS-PAGE, ELISA, Western Blot, qPCR, DLS, IEF, and CE.

o Strong analytical thinking and problem-solving ability.

· Communication & Collaboration:

o Excellent organizational, teamwork, and communication skills.

o Self-motivated with the ability to work independently on R&D projects.

· Other Requirements:

o Occasional travel to headquarters (Massachusetts) and customer sites.

Preferred Skills:

• Experience in mAb upstream bioprocess development (expression, purification, production).

• Familiarity with lab automation and robotic sample prep systems.

• Proficiency with Waters Empower™ and Waters Connect™ software.

• Knowledge of DoE, regression modeling, PCA, and predictive analytics for process optimization.

Diversity and Inclusion:

At Waters, we know that the perfect candidate doesn’t always exist — and we recognize that many talented people hesitate to apply if they don’t meet every single requirement. If you’re excited about this opportunity and have most of the skills or experience we’re looking for, we encourage you to apply. You might be exactly what we need!

We believe strongly in the power of diversity and in creating supportive, inclusive environments where every colleague can thrive. Waters is proud to be an Equal Opportunity Employer, committed to fostering a workplace that celebrates individuality, encourages collaboration, and ensures that everyone has the opportunity to succeed.

Waters Corporation (NYSE:WAT) is a global leader in analytical instruments, separations technologies, and software, serving the life, materials, food, and environmental sciences for over 65 years. Our Company helps ensure the efficacy of medicines, the safety of food and the purity of water, and the quality and sustainability of products used every day. In over 100 countries, our 7,600+ passionate employees collaborate with customers in laboratories, manufacturing sites, and hospitals to accelerate the benefits of pioneering science. 

Diversity and inclusion are fundamental to our core values at Waters Corporation. It benefits our employees, our products, our customers and our community. Waters complies with all applicable federal, state, and local laws. Qualified applicants are considered without regard to sex, race, color, ancestry, national origin, citizenship status, religion, age, marital status (including civil unions), military service, veteran status, pregnancy (including childbirth and related medical conditions), genetic information, sexual orientation, gender identity, legally recognized disability, domestic violence victim status, or any other characteristic protected by law. Waters is proud to be an equal opportunity workplace and is an affirmative action employer. All hiring decisions are based solely on qualifications, merit, and business needs at the time.